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Having been accepted into the Kaede Inn, Nana struggles to find some way to contribute, though she inadvertently brings more trouble than assistance. However, Nana's worries are directed more towards fellow resident Nyu, whom she had only known as Lucy, the violent Diclonius. Fearful that Nyu will unleash the same horrific savagery—violence that scars Nana to this day—upon those close to her, Nana faces a dilemma: attempt to live peacefully alongside Lucy with all the uncertainty that that entails or dispose of the source of her worries, shattering the relationships she has formed at the inn. As Nana struggles to come to a decision, Nyu recalls a painful memory of one of her dearest friends and one of her greatest rivals. [Written by MAL Rewrite]

Lucy is a special breed of human referred to as "Diclonius," born with a short pair of horns and invisible telekinetic hands that lands her as a victim of inhumane scientific experimentation by the government. However, once circumstances present her an opportunity to escape, Lucy, corrupted by the confinement and torture, unleashes a torrent of bloodshed as she escapes her captors. During her breakout, she receives a crippling head injury that leaves her with a split personality: someone with the mentality of a harmless child possessing limited speech capacity. In this state of instability, she stumbles upon two college students, Kouta and his cousin Yuka, who unknowingly take an injured fugitive into their care, unaware of her murderous tendencies. This act of kindness will change their lives, as they soon find themselves dragged into the shadowy world of government secrecy and conspiracy. [Written by MAL Rewrite]